Do you mean the horizontal scroll bar? At 100% zoom, is there any content that is overflowing horizontally? Please let us know the use-case in detail. A few screenshots of the issue would greatly help.
Actually Use case is like for case manager portal which is having screen layout with header left, In that, we are using column menu side bar. In that column menu side bar, column main we are using grid to shown the cases list with around ten column's and in column side bar we are using list of workbaskets. if we can use side bar with 100% zoom then column main having grid is penetrating in to column side bar having workbasket list. Yes, for 100% zoom the content is overflowing horizontally in to other column like workbasket.The grid is not adjusting when we drag the scroll bar horizontally for 100% zoom.