I don't see any notes about explicit support for that version. I see you have opened an SR though and I assume that is because you have that version and something isn't working. Admin's will update this post with any resolution on the SR, so I'll let them update as a resolution comes in.
Not generally. There have been a couple Windows updates in the past that have caused issues with Internet Explorer or with Runtime in general. Those are usually fixed pretty quickly after they have been discovered though. I have not yet been given this update, so I cannot tell you if I have any issues with it. Presumably, the support rep will test and let you know if there are any issues.